Search results for "Research and analysis methods"

showing 10 items of 584 documents

Recombinant laccase from Pediococcus acidilactici CECT 5930 with ability to degrade tyramine

2017

Biogenic amines degradation by bacterial laccases is little known, so we have cloned and heterologously expressed, in E. coli, a new laccase from Pediococcus acidilactici CECT 5930 (Lpa5930), a lactic acid bacterium commonly found in foods able to degrade tyramine. The recombinant enzyme has been characterized by physical and biochemical assays. Here we report the optimization of expression and purification procedures of this laccase. DNA encoding sequence of laccase from P. acidilactici was amplified by PCR and cloned into the expression plasmid pET28a for induction by isopropyl-β-D-thiogalactoipyranoside. Protein expression was performed in E. coli BL21(DE3) harboring pGro7 plasmid expres…

0106 biological sciences0301 basic medicineArabinoseMolecular biologylcsh:MedicineLaccasesBiochemistryBiotecnologia01 natural sciencesSubstrate Specificitylaw.inventionDatabase and Informatics Methodschemistry.chemical_compoundlawRecombinant Protein PurificationCloning MolecularAmineslcsh:Sciencechemistry.chemical_classificationMultidisciplinaryABTSbiologyOrganic CompoundsTemperatureHydrogen-Ion ConcentrationTyramineRecombinant ProteinsEnzymesChemistryRecombination-Based AssayBiochemistryPhysical SciencesRecombinant DNAElectrophoresis Polyacrylamide GelOxidation-ReductionSequence AnalysisResearch ArticleProtein PurificationBioinformaticsTyramineLibrary ScreeningDNA constructionResearch and Analysis Methods03 medical and health sciencesBacterial ProteinsSequence Motif Analysis010608 biotechnologyAmino Acid SequenceBenzothiazolesPediococcus acidilacticiLaccaseMolecular Biology Assays and Analysis TechniquesBase SequenceMolecular massLaccaseOrganic Chemistrylcsh:RChemical CompoundsBiology and Life SciencesProteinsPediococcus acidilacticiSequence Analysis DNAbiology.organism_classificationMolecular biology techniques030104 developmental biologyEnzymechemistryPlasmid ConstructionEnzymologySpectrophotometry Ultravioletlcsh:QSulfonic AcidsEnzimsProteïnesPurification TechniquesPLOS ONE
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Ocean acidification at a coastal CO2 vent induces expression of stress-related transcripts and transposable elements in the sea anemone Anemonia viri…

2019

Published version, available at: https://doi.org/10.1371/journal.pone.0210358 Ocean acidification threatens to disrupt interactions between organisms throughout marine ecosystems. The diversity of reef-building organisms decreases as seawater CO2 increases along natural gradients, yet soft-bodied animals, such as sea anemones, are often resilient. We sequenced the polyA-enriched transcriptome of adult sea anemone Anemonia viridis and its dinoflagellate symbiont sampled along a natural CO2 gradient in Italy to assess stress levels in these organisms. We found that about 1.4% of the anemone transcripts, but only ~0.5% of the Symbiodinium sp. transcripts were differentially expressed. Processe…

0106 biological sciences0301 basic medicineAtmospheric ScienceMolecular biologyMarine and Aquatic SciencesGene ExpressionRetrotransposonSea anemone01 natural sciencesAnemoniaSequencing techniquesMobile Genetic ElementsMultidisciplinarybiologyQREukaryotaOcean acidificationAnemoneRNA sequencingGenomicsChemistryRetrotransposonsPhysical SciencesMedicineTranscriptome AnalysisResearch ArticleScienceZoology010603 evolutionary biology03 medical and health sciencesGreenhouse GasesCnidariaGenetic ElementsSea WaterGeneticsVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470Environmental ChemistryAnimalsMarine ecosystemBiology and life sciencesEcology and Environmental SciencesDinoflagellateChemical CompoundsOrganismsTransposable ElementsCorrectionAquatic EnvironmentsComputational BiologyCarbon Dioxidebiology.organism_classificationGenome AnalysisMarine EnvironmentsInvertebratesVDP::Mathematics and natural science: 400::Basic biosciences: 470Research and analysis methods:Genetikk og genomikk: 474 VDP::Marinbiologi:497 VDP::Økologi:488 [VDP]030104 developmental biologySea AnemonesMolecular biology techniquesAtmospheric ChemistryEarth SciencesSeawater
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Evaluation of chloroplast genome annotation tools and application to analysis of the evolution of coffee species.

2018

International audience; Chloroplast sequences are widely used for phylogenetic analysis due to their high degree of conservation in plants. Whole chloroplast genomes can now be readily obtained for plant species using new sequencing methods, giving invaluable data for plant evolution However new annotation methods are required for the efficient analysis of this data to deliver high quality phylogenetic analyses. In this study, the two main tools for chloroplast genome annotation were compared. More consistent detection and annotation of genes were produced with GeSeq when compared to the currently used Dogma. This suggests that the annotation of most of the previously annotated chloroplast …

0106 biological sciences0301 basic medicineChloroplastsPlant GenomesPlant SciencePlant Genetics01 natural sciencesGenomeCoffeeDatabase and Informatics MethodsPlant GenomicsPlastidsPhylogenyData Management2. Zero hungerPlant evolutionMultidisciplinarybiologyPhylogenetic treeQRfood and beveragesPhylogenetic AnalysisGenome projectGenomicsPhylogenetics[INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA]MedicineEngineering and Technology[INFO.INFO-DC]Computer Science [cs]/Distributed Parallel and Cluster Computing [cs.DC]Cellular Structures and OrganellesCellular TypesSequence AnalysisResearch ArticleBiotechnologyComputer and Information SciencesBioinformaticsSciencePlant Cell BiologyBioengineering[INFO.INFO-SE]Computer Science [cs]/Software Engineering [cs.SE]Coffea canephoraGenes PlantResearch and Analysis Methods010603 evolutionary biology[INFO.INFO-IU]Computer Science [cs]/Ubiquitous ComputingEvolution Molecular[INFO.INFO-CR]Computer Science [cs]/Cryptography and Security [cs.CR]03 medical and health sciencesPhylogeneticsChloroplast GenomePlant CellsGeneticsEvolutionary SystematicsGenome ChloroplastTaxonomyEvolutionary BiologyCoffea arabicaCoffeafungiBiology and Life SciencesComputational BiologyMolecular Sequence AnnotationSequence Analysis DNACell Biology15. Life on landbiology.organism_classificationGenome Analysis[INFO.INFO-MO]Computer Science [cs]/Modeling and SimulationGenome Annotation030104 developmental biologyEvolutionary biology[INFO.INFO-ET]Computer Science [cs]/Emerging Technologies [cs.ET]Plant BiotechnologySequence AlignmentPloS one
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Comparative Mitogenomics of Leeches (Annelida: Clitellata): Genome Conservation and Placobdella-Specific trnD Gene Duplication.

2015

Mitochondrial DNA sequences, often in combination with nuclear markers and morphological data, are frequently used to unravel the phylogenetic relationships, population dynamics and biogeographic histories of a plethora of organisms. The information provided by examining complete mitochondrial genomes also enables investigation of other evolutionary events such as gene rearrangements, gene duplication and gene loss. Despite efforts to generate information to represent most of the currently recognized groups, some taxa are underrepresented in mitochondrial genomic databases. One such group is leeches (Annelida: Hirudinea: Clitellata). Herein, we expand our knowledge concerning leech mitochon…

0106 biological sciences0301 basic medicineClitellatalcsh:MedicineBiochemistry01 natural sciencesGenomeDatabase and Informatics MethodsRNA TransferGene DuplicationGene OrderInvertebrate GenomicsGene duplicationAnnelidslcsh:SciencePhylogenyEnergy-Producing OrganellesData ManagementGeneticseducation.field_of_studyMultidisciplinaryPhylogenetic treePhylogenetic AnalysisGenomicsGenomic DatabasesMitochondriaNucleic acidsPhylogeneticsGenes MitochondrialPlacobdella parasiticaCellular Structures and OrganellesTransfer RNAResearch ArticleComputer and Information SciencesMitochondrial DNAPopulationBioenergeticsBiologyResearch and Analysis Methods010603 evolutionary biologyEvolution MolecularOpen Reading Frames03 medical and health sciencesPhylogeneticsLeechesGeneticsAnimalsEvolutionary Systematics14. Life underwaterCodonMolecular Biology TechniquesNon-coding RNAeducationMolecular BiologyTaxonomyMolecular Biology Assays and Analysis TechniquesEvolutionary Biologylcsh:ROrganismsBiology and Life SciencesComputational BiologyCell BiologyGenome Analysisbiology.organism_classificationInvertebratesBiological Databases030104 developmental biologyAnimal GenomicsGenome MitochondrialRNAlcsh:QPLoS ONE
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Long-Distance Travellers: Phylogeography of a Generalist Parasite, Pholeter gastrophilus, from Cetaceans

2017

We studied the phylogeography and historical demography of the most generalist digenean from cetaceans, Pholeter gastrophilus, exploring the effects of isolation by distance, ecological barriers and hosts' dispersal ability on the population structure of this parasite. The ITS2 rDNA, and the mitochondrial COI and ND1 from 68 individual parasites were analysed. Worms were collected from seven oceanic and coastal cetacean species from the south western Atlantic (SWA), central eastern Atlantic, north eastern Atlantic (NEA), and Mediterranean Sea. Pholeter gastrophilus was considered a single lineage because reciprocal monophyly was not detected in the ML cladogram of all individuals, and seque…

0106 biological sciences0301 basic medicineHeredityTroglotrematidaePopulation Dynamicslcsh:MedicinePopulation geneticsMarine and Aquatic SciencesPathogenesisGeneralist and specialist speciesPathology and Laboratory Medicine01 natural sciencesMonophylyDatabase and Informatics MethodsOceansMedicine and Health Scienceslcsh:ScienceAtlantic OceanMammalseducation.field_of_studyLikelihood FunctionsMultidisciplinaryGeographyReproductive isolationDNA HelminthPhylogeographyGenetic MappingBiogeographyVertebratesHost-Pathogen InteractionsSequence AnalysisResearch ArticleReproductive IsolationBioinformaticsGenetic SpeciationDolphinsPopulationZoologyMarine BiologyBiologyResearch and Analysis Methods010603 evolutionary biology03 medical and health sciencesBodies of waterGeneticsMediterranean SeaAnimalseducationMarine MammalsIsolation by distanceDemographyEvolutionary BiologyAnalysis of VariancePopulation BiologyPilot Whaleslcsh:REcology and Environmental SciencesOrganismsWhalesBiology and Life SciencesGenetic VariationSequence Analysis DNAPhylogeography030104 developmental biologyHaplotypesAmniotesEarth SciencesBiological dispersallcsh:QCetaceaPopulation GeneticsPLoS ONE
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Co-infection with iflaviruses influences the insecticidal properties of Spodoptera exigua multiple nucleopolyhedrovirus occlusion bodies: Implication…

2017

Biological insecticides based on Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) can efficiently control S. exigua larvae on field and greenhouse crops in many parts of the world. Spanish wild populations and laboratory colonies of S. exigua are infected by two iflaviruses (SeIV-1 and SeIV-2). Here we evaluated the effect of iflavirus co-infection on the insecticidal characteristics of SeMNPV occlusion bodies (OBs). Overall, iflavirus co-inoculation consistently reduced median lethal concentrations (LC50) for SeMNPV OBs compared to larvae infected with SeMNPV alone. However, the speed of kill of SeMNPV was similar in the presence or absence of the iflaviruses. A reduction of the we…

0106 biological sciences0301 basic medicineLife CyclesInsecticidesPhysiologyBiosecuritySeMNPV occlusion bodieslcsh:MedicineInsectPathogenesisPathology and Laboratory MedicineWeight Gain01 natural sciencesIflavirus co-infectionLarvaeInvertebrate GenomicsMedicine and Health Scienceslcsh:Sciencemedia_commonLarvaMultidisciplinaryCoinfectionAgricultureGenomicsInsectsPhysiological ParametersAgrochemicalsResearch ArticleArthropodamedia_common.quotation_subjectBiologySpodopteraSpodopteraMicrobiologyLepidoptera genitalia03 medical and health sciencesExtraction techniquesExiguaGeneticsAnimalsPest Control BiologicalBiological InsecticidesInoculationlcsh:RfungiBody WeightOrganismsBiology and Life SciencesPesticidebiology.organism_classificationInvertebratesRNA extractionNucleopolyhedrovirusesResearch and analysis methods010602 entomology030104 developmental biologyBiological insecticidesAnimal Genomicslcsh:QDevelopmental BiologyPLoS ONE
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The role of the Strait of Gibraltar in shaping the genetic structure of the Mediterranean Grenadier, Coryphaenoides mediterraneus, between the Atlant…

2017

24 pages, 4 figures, 4 tables, supplementary information https://dx.doi.org/10.1371/journal.pone.0174988.-- Data Availability: The mtDNA COI sequences can be accessed at BOLD systems through the sample ID: ME-9911; ME-11972; ME-13727; GLF011. New mtDNA COI sequences can be accessed at GenBank by the accession numbers KY345206 - KY345398. GenBank accession numbers for close related species of C. mediterraneus are: Coryphaenoides striaturus - KX656427.1, KX656428.1; Coryphaenoides murray - KX656411.1, KX656410.1; Coryphaenoides carapinus - KX656382.1, KX656381.1; Coryphaenoides brevibarbis - KX656377.1, KX656376.1, KX656375.1. An alignment in fasta with all the haplotypes and respective frequ…

0106 biological sciences0301 basic medicineMediterranean climateLife CyclesHeredityPopulation geneticslcsh:MedicineArtificial Gene Amplification and ExtensionBiochemistryPolymerase Chain Reaction01 natural sciencesBathyal zoneLarvaeMediterranean sealcsh:ScienceAtlantic OceanPrincipal Component Analysiseducation.field_of_studyMultidisciplinaryGeographyMitochondrial DNANucleic acidsGenetic MappingGenetic structureResearch ArticleFish ProteinsGene FlowForms of DNAPopulationZoologyBiologyResearch and Analysis MethodsModels Biological010603 evolutionary biologyElectron Transport Complex IVEvolution Molecular03 medical and health sciencesMediterranean SeaGeneticsAnimalsComputer Simulation14. Life underwaterMolecular Biology TechniqueseducationMolecular BiologyGibraltarEvolutionary BiologyPopulation Biologylcsh:RGenetic VariationBiology and Life SciencesPaleontologyBayes TheoremDNAGenetic divergenceGadiformes030104 developmental biologyHaplotypesGenetic LociEarth SciencesBiological dispersallcsh:QPaleogeneticsPopulation GeneticsMicrosatellite RepeatsDevelopmental BiologyPLoS ONE
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Response to formal comment on Myhrvold (2016) submitted by Griebeler and Werner (2017)

2018

In his 2016 paper, Myhrvold criticized ours from 2014 on maximum growth rates (Gmax, maximum gain in body mass observed within a time unit throughout an individual’s ontogeny) and thermoregulation strategies (ectothermy, endothermy) of 17 dinosaurs. In our paper, we showed that Gmax values of similar-sized extant ectothermic and endothermic vertebrates overlap. This strongly questions a correct assignment of a thermoregulation strategy to a dinosaur only based on its Gmax and (adult) body mass (M). Contrary, Gmax separated similar-sized extant reptiles and birds (Sauropsida) and Gmax values of our studied dinosaurs were similar to those seen in extant similar-sized (if necessary scaled-up) …

0106 biological sciences0301 basic medicineMetabolic AnalysisPhysiologylcsh:MedicineAnimal Phylogenetics01 natural sciencesDinosaursBody TemperatureExtant taxonOrnithologyMaximum gainMedicine and Health SciencesGrowth rateSauropsidalcsh:ScienceArchosauriaData ManagementMammalsMultidisciplinarybiologyVertebrateEukaryotaPrehistoric AnimalsThermoregulationPhylogeneticsBioassays and Physiological AnalysisPhysiological ParametersEctothermVertebratesRegression AnalysisComputer and Information SciencesVertebrate PaleontologyZoologyResearch and Analysis Methods010603 evolutionary biologyFormal CommentBirds03 medical and health sciencesbiology.animalBasal Metabolic Rate MeasurementAnimalsAnimal PhysiologyEvolutionary SystematicsPaleozoologyTaxonomyEvolutionary Biologylcsh:ROrganismsBiology and Life SciencesPaleontologyReptilesbiology.organism_classificationBird Physiology030104 developmental biologyAmniotesEarth Scienceslcsh:QAllometryPaleobiologyZoologyPLoS ONE
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Dinosaur Metabolism and the Allometry of Maximum Growth Rate

2016

In his 2016 paper, Myhrvold criticized ours from 2014 on maximum growth rates (Gmax, maximum gain in body mass observed within a time unit throughout an individual’s ontogeny) and thermoregulation strategies (ectothermy, endothermy) of 17 dinosaurs. In our paper, we showed that Gmax values of similar-sized extant ectothermic and endothermic vertebrates overlap. This strongly questions a correct assignment of a thermoregulation strategy to a dinosaur only based on its Gmax and (adult) body mass (M). Contrary, Gmax separated similar-sized extant reptiles and birds (Sauropsida) and Gmax values of our studied dinosaurs were similar to those seen in extant similar-sized (if necessary scaled-up) …

0106 biological sciences0301 basic medicineMetabolic stateMetabolic AnalysisPhysiologylcsh:MedicineAnimal Phylogenetics01 natural sciencesBody TemperatureDinosaursMathematical and Statistical TechniquesExtant taxonMedicine and Health SciencesBody SizeGrowth ratelcsh:Sciencemedia_commonArchosauriaData ManagementMammalsMultidisciplinaryEcologyFossilsEukaryotaRegression analysisPrehistoric AnimalshumanitiesCurve FittingPhylogeneticsBioassays and Physiological AnalysisPhysiological ParametersEctothermPhysical SciencesVertebratesRegression AnalysisStatistics (Mathematics)Research ArticleComputer and Information Sciencesmedia_common.quotation_subjectVertebrate PaleontologyBiologyResearch and Analysis Methods010603 evolutionary biologyMarsupialsFormal CommentBirds03 medical and health sciencesBasal Metabolic Rate MeasurementAnimalsEvolutionary SystematicsStatistical MethodsPaleozoologyTaxonomyEvolutionary BiologyVariableslcsh:ROrganismsReptilesBiology and Life SciencesPaleontology030104 developmental biologyEvolutionary biologyBasal metabolic rateAmniotesEarth Scienceslcsh:QAllometryPaleobiologyEnergy MetabolismZoologyMathematical FunctionsMathematicsPLoS ONE
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Molecular signatures of silencing suppression degeneracy from a complex RNA virus

2021

As genomic architectures become more complex, they begin to accumulate degenerate and redundant elements. However, analyses of the molecular mechanisms underlying these genetic architecture features remain scarce, especially in compact but sufficiently complex genomes. In the present study, we followed a proteomic approach together with a computational network analysis to reveal molecular signatures of protein function degeneracy from a plant virus (as virus-host protein-protein interactions). We employed affinity purification coupled to mass spectrometry to detect several host factors interacting with two proteins of Citrus tristeza virus (p20 and p25) that are known to function as RNA sil…

0106 biological sciences0301 basic medicineProteomicsCitrusInteraction NetworksPathogenesisPlant Sciencemedicine.disease_causePathology and Laboratory Medicine01 natural sciencesInteractomeBiochemistryBimolecular fluorescence complementationRNA interferenceRNA silencing supressorsCitrus tristeza virusMedicine and Health SciencesDegeneracy (biology)Protein Interaction MapsBiology (General)H20 Plant diseasesPlant ProteinsEcologybiologyPlant virusesEukaryotaArgonautePlantsSmall interfering RNANucleic acidsRNA silencingComputational Theory and MathematicsGenetic interferenceExperimental Organism SystemsModeling and SimulationProteomeArgonaute ProteinsHost-Pathogen InteractionsRNA ViralEpigeneticsResearch ArticleClosterovirusRNA virusViral proteinQH301-705.5Arabidopsis ThalianaPlant PathogensComputational biologyGenome ViralBrassicaResearch and Analysis MethodsModels BiologicalPlant Viral Pathogens03 medical and health sciencesCellular and Molecular NeuroscienceViral ProteinsModel OrganismsPlant and Algal ModelsTobaccomedicineGeneticsGenomesNon-coding RNAProtein InteractionsMolecular signaturesMolecular BiologyEcology Evolution Behavior and SystematicsPlant DiseasesHost Microbial InteractionsBiology and life sciencesMass spectrometryOrganismsComputational BiologyProteinsRNA virusPlant Pathologybiology.organism_classificationGene regulationRepressor Proteins030104 developmental biologyU30 Research methodsAnimal StudiesRNAGene expression010606 plant biology & botanyF30 Plant genetics and breeding
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